Location: Cambridge, MA

Category: Post Doctoral Fellow

Department: Chemical/Biochemical Fingerprinting & Advanced Analytics Group

Position Type: Full-Time

Sanofi is seeking a PhD scientist to join the Chemical/Biochemical Fingerprinting & Advanced Analytics group currently located in Cambridge, Massachusetts. The group belongs to a larger Analytics group, which, combined with Synthesis Development, Biopharmacy, and Early Formulation Development, constitutes the Early Development organization in the US (EDUS) providing the CMC expertise to advance projects from late-stage research through early clinical development up to Phase 2 clinical trials. As part of the Global CMC Development organization, EDUS is striving to become an industry leader in the development of transformative medicines.

Reporting to the Scientific Director of Analytics, the Post Doctoral Scientist is expected to be a major contributor to the establishment and implementation of an advanced attribute monitoring approach by applying chemical fingerprinting techniques such as global profiling by LC-High Resolution Mass Spectrometry and data processing platform/databases for streamlined identification of impurities, degradants and profiling of complex excipients.  Work entails a balance of method development and design of data processing tools and databases. It involves close collaboration with Sanofi groups in the US and Globally, as well as our partners in academia and the software vendor. The project is planned for a 2-year term with a possibility of extension for a 3-rd year and is expected to produce analytical and digital tools for advanced and streamlined characterization of impurities, and degradants and for evaluation/selection of synthetic routes with the goal of prediction and minimization of potential liabilities and is expected to result in publications.